Wickramasinghe S N, Longland J E
Br Med J. 1974 Jul 20;3(5924):148-50. doi: 10.1136/bmj.3.5924.148.
Deoxyuridine (dU) suppression tests have been performed on virtually all marrow samples aspirated at this hospital over the past 12 months. Of the 110 samples studied 26 gave abnormal results, and these 26 samples came from patients deficient in either vitamin B(12) or folate. The dU suppression test was found to be of particular value in the diagnosis of vitamin B(12) or folate deficiency in non-anaemic patients with macrocytosis and equivocal changes in marrow morphology and in patients in whom the serum vitamin B(12) or red cell folate levels were within the normal range.
在过去12个月里，本院对几乎所有采集的骨髓样本都进行了脱氧尿苷（dU）抑制试验。在研究的110份样本中，有26份结果异常，这26份样本来自维生素B12或叶酸缺乏的患者。发现dU抑制试验对于诊断非贫血性大细胞增多症患者且骨髓形态有不明确变化以及血清维生素B12或红细胞叶酸水平在正常范围内的患者的维生素B12或叶酸缺乏具有特殊价值。
