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[葡萄蜗牛条件反射形成初期指挥神经元兴奋性的变化]

[Changes in the excitability of command neurons during the initial period of conditioned reflex formation in grape snails].

作者信息

Litvinov E G, Logunov D B

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1979 Mar-Apr;29(2):284-94.

PMID:452718
Abstract

The procedure of elaboration of conditioned defensive pneumostomum closure was reproduced in neurophysiological experiments on half-intact preparation of the snail. Activity of identified command neurones involved in the reinforcing unconditioned reflex, was recorded intracellularly. Conditioned and unconditioned stimuli converged on these neurones. Excitability of the explored command neurones increased during the first stages of conditioning. Appearance and consequent intensification of the initially absent spike response to the conditioned stimulus was essentially due to this excitability change. Command neurones action potentials evoked by the conditioned stimulus elicited some effector reactions which were the first signs of conditioning. The conclusion is made that the excitability changes in certain nerve cells are essential for determining the initial phase of conditioning.

摘要

在蜗牛半离体标本的神经生理学实验中,重现了条件性防御性呼吸孔关闭的形成过程。对参与强化非条件反射的已识别指令神经元的活动进行了细胞内记录。条件刺激和非条件刺激都作用于这些神经元。在条件反射形成的最初阶段,所研究的指令神经元的兴奋性增加。对条件刺激最初不存在的峰电位反应的出现及随后的增强,主要是由于这种兴奋性变化。由条件刺激诱发的指令神经元动作电位引发了一些效应反应,这些反应是条件反射的最初迹象。得出的结论是,某些神经细胞的兴奋性变化对于确定条件反射的初始阶段至关重要。

相似文献

1
[Changes in the excitability of command neurons during the initial period of conditioned reflex formation in grape snails].[葡萄蜗牛条件反射形成初期指挥神经元兴奋性的变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1979 Mar-Apr;29(2):284-94.
2
[The active electrogenesis of the command neurons in the defensive behavior of the mollusk during conditioning].[条件反射期间软体动物防御行为中指令神经元的主动电发生]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 Jul-Aug;41(4):781-7.
3
[Nonspecific changes in the response of command neurons in Helix leucorum L. to a combination of 2 stimuli].[白旋螺中指令神经元对两种刺激组合反应的非特异性变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1983 May-Jun;33(3):543-50.
4
[Duration of changes in electrical characteristics of command neurons after defensive conditioning in snails].[蜗牛防御性条件反射后指令神经元电特性变化的持续时间]
Zh Vyssh Nerv Deiat Im I P Pavlova. 2003 May-Jun;53(3):379-82.
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[Formation of the defensive response to the time in snails during rhythmic stimulation of an individual command neuron].[在单个指令神经元的节律性刺激期间蜗牛对时间的防御反应的形成]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1982;32(5):908-14.
6
[The electrical characteristics of the command and motor neurons during the acquisition of a conditioned defensive reflex and the development of long-term sensitization in snails].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1998 Nov-Dec;48(6):1004-13.
7
[Command neurons in the unconditioned reflex arc of the grape snail].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 May-Jun;27(3):538-44.
8
[Electrophysiological study of effects of chronic injection of caffeine on defensive reflex conditioning in grape snail].
Zh Vyssh Nerv Deiat Im I P Pavlova. 2008 Mar-Apr;58(2):202-8.
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[Formation of a conditioned defense reflex in edible snails and changes in command neuron activity].[可食用蜗牛中条件防御反射的形成及指挥神经元活动的变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 Sep-Oct;30(5):1003-11.
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[Modeling the "conditioned" response of command neurons on the isolated CNS of grape snails].
Dokl Akad Nauk SSSR. 1979;246(3):750-2.

引用本文的文献

1
The electrical characteristics of command and motor neurons during acquisition of a conditioned defensive reflex and formation of long-term sensitization in snails.蜗牛在获得条件性防御反射和形成长期敏感化过程中指令神经元和运动神经元的电特性。
Neurosci Behav Physiol. 2000 Jan-Feb;30(1):81-8. doi: 10.1007/BF02461395.
2
Changes in the electrical characteristics of command neurons on development of a conditioned defensive reflex in the edible snail.
Neurosci Behav Physiol. 1997 Jul-Aug;27(4):367-9. doi: 10.1007/BF02462937.
3
Action of vasopressin analog on neuronal excitability in Helix lucorum.血管加压素类似物对福寿螺神经元兴奋性的作用。
Neurosci Behav Physiol. 1987 Sep-Oct;17(5):407-14. doi: 10.1007/BF01188730.