Tsementzis S A, Gillingham F J, Hitchcock E R, Gordon A
Acta Neurochir (Wien). 1979;46(1-2):5-43. doi: 10.1007/BF01407678.
The mechanical effect of acute decerebrate rigidity upon the ICP and the mechanisms underlying the relationship between them have been investigated with experiments performed on 26 cats. It has been shown that: a) Extreme rigidity of the peripheral musculature with or without partial activation of the trunkal muscles produces no change in ICP, b) the simultaneous elevation of the intra-thoracic and intra-abdominal pressures is the factor primarily operative in raising and maintaining the elevated ICP, c) when cerebrovascular homeostasis is already defective a subsidiary but not unimportant role is played by the elevation of the systemic arterial pressure, d) under conditions of normal brain elastance mild and short-lasting spasms produce no effect on the ICP. In an animal, however, in which the brain elastance had been increased by inflating a small air-filled balloon, similar spasms produced a marked increase in ICP.
通过对26只猫进行的实验，研究了急性去大脑强直对颅内压（ICP）的机械作用及其两者关系的潜在机制。结果表明：a）外周肌肉组织的极度强直，无论躯干肌肉是否部分激活，均不会引起ICP变化；b）胸腔和腹腔压力同时升高是导致并维持ICP升高的主要因素；c）当脑血管自身调节功能已受损时，体循环动脉压升高起辅助但并非不重要的作用；d）在脑弹性正常的情况下，轻度和短暂的痉挛对ICP无影响。然而，在通过向一个小气球内充气使脑弹性增加的动物中，类似的痉挛会使ICP显著升高。
