[采用非水滴定法分析吩噻嗪类抗精神病药物]
[Analysis of phenothiazine neuroleptics by means of non-aqueous titrimetry].
作者信息
Barbato F, Cozzolino A, Silipo C, Vittoria A
出版信息
Boll Soc Ital Biol Sper. 1979 Oct 15;55(19):2012-8.
PMID:45304
Abstract
Phenothiazine neuroleptic drugs, either as pure compounds or in pharmaceutical dosage forms have been quantitatively assayed by nonaqueous titrimetry. Suggested procedure is applicable to basic drugs and their corresponding salts without prior cleanup overcoming the interferences due to excipients.
摘要
吩噻嗪类抗精神病药物，无论是作为纯化合物还是制成药物剂型，均已通过非水滴定法进行了定量测定。建议的方法适用于碱性药物及其相应盐类，无需预先净化即可克服辅料带来的干扰。
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