Giaever I, Laffin R J
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4533-5. doi: 10.1073/pnas.71.11.4533.
When the hepatitis B antigen is first adsorbed on a specially prepared metal surface, the subsequent reaction with its specific antibody produces complexes that are visible to the unaided eye. Application of this principle has led to the development of tests for both antigen and antibody that compare favorably with the sensitivity obtained by radioimmunoassay.
当乙肝抗原首次吸附在特制的金属表面时，其随后与特异性抗体的反应会产生肉眼可见的复合物。这一原理的应用导致了抗原和抗体检测方法的发展，这些方法与放射免疫测定法所获得的灵敏度相比毫不逊色。
