Greco R S
Am J Surg. 1979 Jun;137(6):752-6. doi: 10.1016/0002-9610(79)90087-4.
Twenty-two patients with cancer of the colon and rectum were evaluated before and after surgical treatment by leukocyte migration inhibition assays using autologous and allogeneic tumor extracts. All patients were resected for cure. Patients with cancer of the colon demonstrated significant migration inhibition against autologous extracts before surgery and in the immediate postoperative period. Patients with rectal cancer did not demonstrate significant migration inhibition at any time. The possibility that immunity plays a role in the poorer prognosis of patients with rectal cancer is discussed.
对22例结肠直肠癌患者在手术治疗前后，使用自体和同种异体肿瘤提取物通过白细胞迁移抑制试验进行评估。所有患者均接受了根治性切除。结肠癌患者在手术前和术后即刻对自体提取物表现出显著的迁移抑制。直肠癌患者在任何时候均未表现出显著的迁移抑制。文中讨论了免疫在直肠癌患者预后较差中发挥作用的可能性。
