印度马哈拉施特拉邦那格浦尔市1965年发热疾病流行的病因
Etiology of the 1965 epidemic of febrile illness in Nagpur city, Maharashtra State, India.
作者信息
Rodrigues F M, Patankar M R, Banerjee K, Bhatt P N, Goverdhan M K, Pavri K M, Vittal M
出版信息
Bull World Health Organ. 1972;46(2):173-9.
An investigation of an extensive outbreak of febrile illness during the months of April, May, and June 1965, in the city of Nagpur, Maharashtra State, showed that the main etiological agent was chikungunya virus. Dengue type 4 and Chandipura viruses were also active during this period. In all, 26 strains of virus were isolated from 60 acute phase human sera, and of these strains, 23 were identified as chikungunya virus, 2 as Chandipura, and 1 as dengue type 4. Five strains of chikungunya virus and 9 strains of dengue type 4 virus were isolated from 34 pools of Aedes aegypti collected from the affected areas. Results of complement fixation tests with acute-convalescent paired serum samples and single convalescent sera confirmed that chikungunya virus was the main etiological agent. The significance of these findings is discussed.
1965年4月、5月和6月期间，对马哈拉施特拉邦那格浦尔市大规模发热疾病爆发进行的一项调查显示，主要病原体是基孔肯雅病毒。4型登革热病毒和钱迪普拉病毒在此期间也很活跃。总共从60份急性期人类血清中分离出26株病毒，其中23株被鉴定为基孔肯雅病毒，2株为钱迪普拉病毒，1株为4型登革热病毒。从受影响地区采集的34池埃及伊蚊中分离出5株基孔肯雅病毒和9株4型登革热病毒。急性恢复期配对血清样本和单一恢复期血清的补体结合试验结果证实，基孔肯雅病毒是主要病原体。讨论了这些发现的意义。
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