Waldman R H, Cruz J M, Rowe D S
Clin Exp Immunol. 1972 Sep;12(1):49-54.
Antisperm activity was detected in cervicovaginal secretions from some normal women, and more frequently in women with sterility of unknown etiology and in pregnant women, particularly in the early months of pregnancy. This antisperm activity was detected using the technique of inhibition of the migration of sperm up a capillary tube. This activity was removed with anti-IgM antiserum but not with anti-IgA or anti-IgG sera. The activity eluted from a Sephadex G-200 column with the excluded volume. This is felt to be presumptive evidence that there is, in cervicovaginal secretions, antibody to antigens on the surface of sperm. There is evidence that this antibody was locally produced since serum from the same individuals did not have the sperm inhibiting activity.
在一些正常女性的宫颈阴道分泌物中检测到了抗精子活性，在不明原因不孕的女性和孕妇中更常见，尤其是在妊娠早期。这种抗精子活性是通过抑制精子在毛细管中迁移的技术检测到的。这种活性可被抗IgM抗血清去除，但不能被抗IgA或抗IgG血清去除。该活性从Sephadex G - 200柱上以排阻体积洗脱。这被认为是宫颈阴道分泌物中存在针对精子表面抗原的抗体的初步证据。有证据表明这种抗体是局部产生的，因为同一个体的血清没有精子抑制活性。
