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1
Progressive hypogammaglobulinaemia in a child born to a mother with Hodgkin's disease.一位患有霍奇金病的母亲所生儿童出现的进行性低丙种球蛋白血症。
Arch Dis Child. 1979 Apr;54(4):313-5. doi: 10.1136/adc.54.4.313.
2
Non-invasive detection of genomic imbalances in Hodgkin/Reed-Sternberg cells in early and advanced stage Hodgkin's lymphoma by sequencing of circulating cell-free DNA: a technical proof-of-principle study.通过循环游离DNA测序对早期和晚期霍奇金淋巴瘤中霍奇金/里德-斯腾伯格细胞的基因组失衡进行无创检测：一项原理验证技术研究。
Lancet Haematol. 2015 Feb;2(2):e55-65. doi: 10.1016/S2352-3026(14)00039-8. Epub 2015 Jan 20.
3
Hodgkin's disease in siblings: a family study.
Oncology. 1976;33(3):116-8. doi: 10.1159/000225123.
4
[Hodgkin's disease and pregnancy].[霍奇金淋巴瘤与妊娠]
Rev Med Univ Navarra. 1988 Oct-Dec;32(4):201-3.
5
[Cancer and primary humoral immunodeficiency].[癌症与原发性体液免疫缺陷]
Bull Cancer. 1997 Aug;84(8):813-21.
6
Immunological deficiency diseases. Agammaglobulinemia, hypogammaglobulinemia, Hodgkin's disease and sarcoidosis.免疫缺陷疾病。无丙种球蛋白血症、低丙种球蛋白血症、霍奇金病和结节病。
Prog Allergy. 1962;6:187-319.
7
Hodgkin's disease associated with IgA and IgG subclass deficiency.霍奇金淋巴瘤与IgA和IgG亚类缺陷相关。
J Intern Med. 1996 Aug;240(2):99-102. doi: 10.1046/j.1365-2796.1996.514837000.x.
8
HODGKIN'S DISEASE AND HYPOGAMMAGLOBULINAEMIA: A RARE ASSOCIATION.霍奇金淋巴瘤与低丙种球蛋白血症：一种罕见的关联。
Br Med J. 1964 May 2;1(5391):1156-8. doi: 10.1136/bmj.1.5391.1156.
9
[Simultaneous occurrence in a family of malignant lymphomas, agammaglobulinemia, and hemophilia A].
J Genet Hum. 1973 Jun;21(2):85-138.
10
Immunoglobulin A deficiency on serological coeliac screening: an opportunity for early diagnosis of hypogammaglobulinaemia.血清学乳糜泻筛查中的免疫球蛋白 A 缺乏症：早期诊断低丙种球蛋白血症的机会。
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本文引用的文献

1
Marital Hodgkin's disease; a review of the familial incidence and of etiological factors.婚姻与霍奇金病；家族发病率及病因学因素综述
AMA Arch Intern Med. 1951 Dec;88(6):819-30. doi: 10.1001/archinte.1951.03810120120012.
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[Congenital immunological paresis in the absence of specific beta 2-globulin & normal quantities of gamma-globulin].
Helv Paediatr Acta. 1957 Aug;12(3):241-59.
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[Lymphogranulomatosis and pregnancy].[淋巴肉芽肿病与妊娠]
Arch Klin Med. 1967 Sep 11;213(4):255-77.
4
Circulating B-cells in patients with immunodeficiency.免疫缺陷患者体内的循环B细胞。
Am J Pathol. 1972 Dec;69(3):513-28.
5
Lymphoreticular malignancies and immunologic abnormalities in a sibship.一个家族中的淋巴网状系统恶性肿瘤和免疫异常
Am J Med. 1971 Jan;50(1):42-8. doi: 10.1016/0002-9343(71)90203-8.
6
Antibody deficiency and alopecia.抗体缺乏与脱发
J Pediatr. 1976 Nov;89(5):728-31. doi: 10.1016/s0022-3476(76)80791-3.
7
Common variable immunodeficiency, Hodgkin's disease, and other malignancies in a Newfoundland family.
Lancet. 1975 Jan 25;1(7900):195-7. doi: 10.1016/s0140-6736(75)91361-6.

一位患有霍奇金病的母亲所生儿童出现的进行性低丙种球蛋白血症。

Progressive hypogammaglobulinaemia in a child born to a mother with Hodgkin's disease.

作者信息

Evans D I, Burn J L

出版信息

Arch Dis Child. 1979 Apr;54(4):313-5. doi: 10.1136/adc.54.4.313.

DOI:10.1136/adc.54.4.313
PMID:453917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1545314/
Abstract

A young woman developed Hodgkin's disease (nodular sclerosis) in pregnancy and gave birth to a boy who developed common variable immunodeficiency. Initially there was normal IgG with low IgA and IgM, and antibody deficiency. IgG levels fell progressively over 4 years. Cellular immunity was normal. We suggest that this is a further family with immune deficiency presenting with common variable immunodeficiency and lymphoid malignancy.

摘要

一名年轻女性在孕期患上霍奇金病（结节硬化型），并生下一名患有常见变异型免疫缺陷病的男孩。起初，其IgG水平正常，IgA和IgM水平低，且存在抗体缺陷。IgG水平在4年中逐渐下降。细胞免疫正常。我们认为这是又一个出现常见变异型免疫缺陷病和淋巴系统恶性肿瘤的免疫缺陷家族。