[利用5-溴脱氧尿苷（BUDR）和可控热变性的解螺旋方法对X染色体进行鉴别] - Suppr

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超能文献

[Differentiation of X chromosomes by despiralization methods using 5-bromodeoxyuridine (BUDR) and controlled thermal denaturation].

作者信息

Baranovskaya L T, Zakharov A F, Dutrillaux B, Carpentier S, Prieur M, Lejeune J

出版信息

Ann Genet. 1972 Dec;15(4):271-4.

PMID:4539487

Abstract

摘要

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[Differentiation of X chromosomes by despiralization methods using 5-bromodeoxyuridine (BUDR) and controlled thermal denaturation].[利用5-溴脱氧尿苷（BUDR）和可控热变性的解螺旋方法对X染色体进行鉴别]

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H3-deoxycytidine incorporation into X-chromosomes differentially condensed under 5-bromodeoxyuridine treatment in cases of 49,XXXXY, 48,XXXX, 47,XXX, 46,X,i(Xq), and 45,X-46,X,i(Xq).在49,XXXXY、48,XXXX、47,XXX、46,X,i(Xq)和45,X - 46,X,i(Xq)病例中，在5 - 溴脱氧尿苷处理下，H3 - 脱氧胞苷掺入差异凝聚的X染色体中。

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Structural X-chromosome abnormality in a female with gonadal dysgenesis.一名患有性腺发育不全的女性的X染色体结构异常。

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