Tsvetkova G M, Persina I S, Lezvinskaia E M
Arkh Patol. 1979;41(5):30-7.
Histological and electron microscopic examination of changes in the skin and blood revealed three different stages in the development of experimental allergic contact dermatitis (ACD). The primary contact reaction (24 hours) had features of nonspecific inflammation with some morphological signs of initial sensitization. Inflammation in the flare-up reaction (5-7 days) is the result of the immune process, and basophilic infiltration of the skin is the obligatory component of this reaction. ACD (patch test at 15 days) was shown to have morphological manifestations typical of the delayed type hypersensitivity and some signs of the immediate type reactions.
对皮肤和血液变化进行的组织学及电子显微镜检查揭示了实验性变应性接触性皮炎（ACD）发展过程中的三个不同阶段。初次接触反应（24小时）具有非特异性炎症的特征以及一些初始致敏的形态学迹象。激发反应（5 - 7天）中的炎症是免疫过程的结果，皮肤的嗜碱性浸润是该反应的必备成分。变应性接触性皮炎（15天的斑贴试验）显示出具有迟发型超敏反应典型的形态学表现以及一些速发型反应的迹象。
