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[颅脑低温灌注对缺血性脑代谢的影响]

[Effect of craniocerebral hypothermic perfusion on the metabolism of ischemic brain].

作者信息

Radushkevich V L, Malyshev V V, Aleksanov A A

出版信息

Biull Eksp Biol Med. 1979 May;87(5):410-2.

PMID:454814
Abstract

Intravascular perfusion of the brain by colloid-saline "extracellular" fluid was carried out in 58 experimental dogs against the background of acute hypoxia. Biochemical indices of metabolism in flowing and outflowing brain fluid as well as in the brain tissue were studied. It was shown that under conditions of acute hypoxia normo- and particularly hypothermic intravascular perfusion of the brain by colloid-saline fluid decreases the disturbances of metabolic homeostasis.

摘要

在58只实验犬急性缺氧的背景下,用胶体盐“细胞外”液对大脑进行血管内灌注。研究了流入和流出脑液以及脑组织中代谢的生化指标。结果表明,在急性缺氧条件下,用胶体盐液对大脑进行正常体温尤其是低温血管内灌注可减少代谢稳态的紊乱。

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