对由卡巴胆碱去极化的肌纤维中氯离子活性的直接估计。
Direct estimates of chloride activity in muscle fibres depolarized by carbachol.
作者信息
Feltz A, Jaoul A
出版信息
Br J Pharmacol. 1974 Jun;51(2):304-6. doi: 10.1111/j.1476-5381.1974.tb09661.x.
Abstract
Intracellular chloride activities have been measured in muscle fibres with chloride-sensitive electrodes. It was found that the depolarization induced by carbachol produces an influx of chloride ions, the accumulation of which leads to further sustained depolarization. The present study thus confirms the evidence put forward by Jenkinson & Terrar (1973) of an influence of chloride ions on the membrane potential after a prolonged application of carbachol.
摘要
已使用氯化物敏感电极测量了肌肉纤维中的细胞内氯化物活性。结果发现，卡巴胆碱诱导的去极化会导致氯离子内流，其积累会导致进一步的持续去极化。因此，本研究证实了詹金森和泰拉（1973年）提出的关于长时间应用卡巴胆碱后氯离子对膜电位有影响的证据。
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