Adkins B L, Barmes D E, Schamschula R G
Bull World Health Organ. 1974;50(6):495-504.
Samples of urine obtained from 10 adult people in each of 10 selected villages in the Sepik district of New Guinea were analysed to determine the levels of 19 elements thought to be of possible relevance to the prevalence of dental caries, judged by the results of previous research. Subjects with dental caries experience could be distinguished from those who are caries-free on the basis of the content of urine samples, as evidenced by the calculation of a statistically significant discriminant function. The elements most likely to be meaningful in relation to such discrimination are molybdenum, magnesium, copper, lead, phosphorus, strontium, and possibly zirconium and potassium. The concentrations of magnesium and phosphorus were significantly correlated with a number of other elements in the samples. Fluorine appears to have a considerable bearing on the output of magnesium, phosphorus, strontium, zinc, and calcium, the first four of which were named above as being major determinants in the discriminant function.
从新几内亚塞皮克地区10个选定村庄的每个村庄中选取10名成年人，采集其尿液样本进行分析，以确定19种元素的含量。根据以往研究结果判断，这些元素可能与龋齿患病率相关。通过计算具有统计学意义的判别函数证明，根据尿液样本的含量，可以区分有龋齿经历的受试者和无龋齿的受试者。与这种区分最有可能相关的元素是钼、镁、铜、铅、磷、锶，可能还有锆和钾。样本中镁和磷的浓度与许多其他元素显著相关。氟似乎与镁、磷、锶、锌和钙的排出量有相当大的关系，其中前四种元素在上述判别函数中被列为主要决定因素。
