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Aerobic reduction of cytochrome b 566 in pigeon-heart mitochondria (succinate-cytochrome C1 reductase-stopped-flow kinetics).鸽心线粒体中细胞色素b 566的需氧还原(琥珀酸-细胞色素C1还原酶-停流动力学)
Proc Natl Acad Sci U S A. 1972 Jan;69(1):50-4. doi: 10.1073/pnas.69.1.50.
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Interactions of uncoupling agents and of antimycin A with cytochrome b in yeast and heart muscle preparation under anaerobic conditions.在厌氧条件下,解偶联剂和抗霉素A与酵母和心肌制剂中细胞色素b的相互作用。
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鸽心线粒体中细胞色素b 566的需氧还原(琥珀酸-细胞色素C1还原酶-停流动力学)

Aerobic reduction of cytochrome b 566 in pigeon-heart mitochondria (succinate-cytochrome C1 reductase-stopped-flow kinetics).

作者信息

Erecińska M, Chance B, Wilson D F, Dutton P L

出版信息

Proc Natl Acad Sci U S A. 1972 Jan;69(1):50-4. doi: 10.1073/pnas.69.1.50.

DOI:10.1073/pnas.69.1.50
PMID:4550509
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC427542/
Abstract

In anaerobic, uncoupled pigeon-heart mitochondria treated with oxidizable substrate, the cytochrome b(566) remains largely oxidized. In the presence of antimycin A, addition of oxygen induces a reduction of this cytochrome. The rate of cytochrome b(566) reduction is comparable to and dependent on the rate of cytochrome c(1) oxidation. Kinetic data suggest that either ubiquinone or another donor of similar potential provides electrons for the reduction of cytochrome b(566). It is postulated that the aerobic reduction of cytochrome b(566) is directly related to the energy conservation at site II.

摘要

在用可氧化底物处理的厌氧、解偶联鸽心线粒体中,细胞色素b(566)大部分保持氧化状态。在抗霉素A存在的情况下,加入氧气会导致该细胞色素还原。细胞色素b(566)的还原速率与细胞色素c1的氧化速率相当且依赖于后者。动力学数据表明,泛醌或另一种具有类似电位的供体为细胞色素b(566)的还原提供电子。据推测,细胞色素b(566)的需氧还原与位点II处的能量守恒直接相关。