Mashalay M M, Proudman J A, Wentworth B C
Br Poult Sci. 1979 Jan;20(1):19-26. doi: 10.1080/00071667908416545.
Large White turkey hens were implanted with silicone capsules containing either cholesterol (control), progesterone, 17-beta oestradiol (E2), oestrone (E1) or a combination of progesterone and E2. Egg production and fertility were measured. Blood samples were collected weekly for measurement of progesterone by radioimmunoassay. 2. Progesterone alone caused a several-fold increase in serum progesterone concentrations initially and significantly depressed egg production. Simultaneous administration of E2 significantly decreased progesterone concentration, but did not ameliorate the decrease in egg production. 3. There were significant positive correlations between serum progesterone concentration and egg production in control birds and those receiving E2 and E1. There was no significant correlation between progesterone concentration and fertility. 4. The results indicated that, within the physiological range, higher progesterone concentrations are associated with higher egg production. However, maintenance of constant progesterone concentrations throughout the reproductive season by means of implants was not achieved. Implants of E1 and E2 did not affect fecundity.
将大型白色火鸡母鸡植入含有胆固醇（对照）、孕酮、17-β雌二醇（E2）、雌酮（E1）或孕酮与E2组合的硅胶胶囊。测量产蛋量和受精率。每周采集血样，通过放射免疫测定法测量孕酮。2.单独使用孕酮最初会使血清孕酮浓度增加几倍，并显著降低产蛋量。同时给予E2可显著降低孕酮浓度，但并未改善产蛋量的下降。3.对照鸡以及接受E2和E1的鸡的血清孕酮浓度与产蛋量之间存在显著正相关。孕酮浓度与受精率之间无显著相关性。4.结果表明，在生理范围内，较高的孕酮浓度与较高的产蛋量相关。然而，通过植入物在整个繁殖季节维持恒定的孕酮浓度并未实现。E1和E2的植入物不影响繁殖力。
