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成年犬心丝虫（恶丝虫）的己糖激酶

Hexokinase of the adult dog heartworm, Dirofilaria immitis.

作者信息

Hutchison W F, Turner A C, Oelshlegel F J

机构信息

Department of Preventive Medicine, University of Mississippi School of Medicine, Jackson 39216.

出版信息

Comp Biochem Physiol B. 1977;58(2):131-4. doi: 10.1016/0305-0491(77)90097-9.

DOI:10.1016/0305-0491(77)90097-9
PMID:45524
Abstract
  1. Dirofilaria immitis hexokinase was relatively heat stable and had a pH optimum range between 7.8 and 8.2. 2. Mean Vmax was 0.40 +/- 0.10 (S.D.) mumole/min/100 mg of worm. 3. Mean Km values were 0.32 mM for glucose, 0.86 mM for fructose and 0.39 mM for ATP. 4. Glucose-6-phosphate was not a strong product inhibitor. 5. Starch gel electrophoresis demonstrated at least three isozymes.
摘要
  1. 犬恶丝虫己糖激酶相对耐热，最适pH范围在7.8至8.2之间。2. 平均最大反应速度（Vmax）为0.40±0.10（标准差）微摩尔/分钟/100毫克虫体。3. 葡萄糖的平均米氏常数（Km）值为0.32毫摩尔，果糖为0.86毫摩尔，三磷酸腺苷（ATP）为0.39毫摩尔。4. 6-磷酸葡萄糖不是强产物抑制剂。5. 淀粉凝胶电泳显示至少有三种同工酶。

相似文献

1
Hexokinase of the adult dog heartworm, Dirofilaria immitis.成年犬心丝虫（恶丝虫）的己糖激酶
Comp Biochem Physiol B. 1977;58(2):131-4. doi: 10.1016/0305-0491(77)90097-9.
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Parasite-specific inhibition of 5'-nucleotidase from Onchocerca volvulus and Dirofilaria immitis by the amoscanate-derivative CGP 8065.
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Glycosyl transferase activity in homogenates of adult Dirofilaria immitis.成年犬恶丝虫匀浆中的糖基转移酶活性。
Mol Biochem Parasitol. 1982 Jan;5(1):19-31. doi: 10.1016/0166-6851(82)90003-2.
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Phosphofructokinase from Dirofilaria immitis. Stimulation of activity by phosphorylation with cyclic AMP-dependent protein kinase.犬恶丝虫的磷酸果糖激酶。环磷酸腺苷依赖性蛋白激酶磷酸化对其活性的刺激作用。
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Acid phosphatase activity demonstrated in the nematodes, Dirofilaria immitis and Angiostrongylus cantonensis with special reference to the characters and distribution.在犬恶丝虫和广州管圆线虫中显示的酸性磷酸酶活性，特别提及特征和分布。
Parasitology. 1980 Feb;80(1):23-38. doi: 10.1017/s0031182000000482.
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Proteolytic cleavage of IgG and other protein substrates by Dirofilaria immitis microfilarial enzymes.犬恶丝虫微丝蚴酶对IgG及其他蛋白质底物的蛋白水解切割作用。
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Isolation, partial purification and some properties of two acid proteases from adult Dirofilaria immitis.来自成年犬恶丝虫的两种酸性蛋白酶的分离、部分纯化及某些特性
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