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对所选噬菌体脱氧核糖核酸中核苷酸分布和常见序列的比较。

Comparisons of the distribution of nucleotides and common sequences in deoxyribonucleic acid from selected bacteriophages.

作者信息

Skalka S A, Hanson P

出版信息

J Virol. 1972 Apr;9(4):583-93. doi: 10.1128/JVI.9.4.583-593.1972.

DOI:10.1128/JVI.9.4.583-593.1972
PMID:4553679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC356342/
Abstract

Results from comparisons of deoxyribonucleic acid (DNA) from several classes of bacteriophages suggest that most phage chromosomes contain either a homogeneous distribution of nucleotides or are made up of a few, rather large segments of different quanine plus cytosine (G + C) contents which are internally homogeneous. Among those temperate phages tested, most contained segmented DNA. Comparisons of sequence similarities among segments from lambdoid phage DNA species revealed the following order in relatedness to lambda: 82 (and 434) > 21 > 424 > phi80. Most common sequences are found in the highest G + C segments, which in lambda contain head and tail genes. Hybridization tests with lambda and 186 or P2 DNA species verified that the lambdoids and 186 and P2 belong to two distinct groups. There are fewer homologous sequences between the DNA species of coliphages lambda and P2 or 186 than there are between the DNA species of coliphage lambda and salmonella phage P22.

摘要

对几类噬菌体的脱氧核糖核酸(DNA)进行比较的结果表明,大多数噬菌体染色体要么含有均匀分布的核苷酸,要么由少数几个不同鸟嘌呤加胞嘧啶(G + C)含量的相当大的片段组成,这些片段在内部是均匀的。在测试的那些温和噬菌体中,大多数含有分段DNA。对λ样噬菌体DNA物种各片段之间序列相似性的比较揭示了与λ的亲缘关系顺序如下:82(和434)> 21 > 424 > φ80。最常见的序列存在于G + C含量最高的片段中,在λ中这些片段包含头部和尾部基因。用λ与186或P2 DNA物种进行的杂交试验证实,λ样噬菌体与186和P2属于两个不同的组。大肠杆菌噬菌体λ与P2或186的DNA物种之间的同源序列比大肠杆菌噬菌体λ与沙门氏菌噬菌体P22的DNA物种之间的同源序列少。

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Comparisons of the distribution of nucleotides and common sequences in deoxyribonucleic acid from selected bacteriophages.对所选噬菌体脱氧核糖核酸中核苷酸分布和常见序列的比较。
J Virol. 1972 Apr;9(4):583-93. doi: 10.1128/JVI.9.4.583-593.1972.
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本文引用的文献

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THE STRUCTURAL GENE FOR lambda EXONUCLEASE.λ核酸外切酶的结构基因。
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