氨甲环酸用于控制血友病和克里斯马斯病患者拔牙后的出血。
Tranexamic acid in control of haemorrhage after dental extraction in haemophilia and Christmas disease.
作者信息
Forbes C D, Barr R D, Reid G, Thomson C, Prentice C R, McNicol G P, Douglas A S
出版信息
Br Med J. 1972 May 6;2(5809):311-3. doi: 10.1136/bmj.2.5809.311.
Abstract
In a double-blind trial tranexamic acid (AMCA, Cyclokapron), 1 g three times a day for five days, significantly reduced blood loss and transfusion requirements after dental extraction in patients with haemophilia and Christmas disease. No side effects were seen in either group of patients. Screening tests showed no toxic action of tranexamic acid on the liver, kidney, or heart.
摘要
在一项双盲试验中，氨甲环酸（抗血纤溶环酸，止血环酸），每天三次，每次1克，连续服用五天，显著减少了血友病和克里斯马斯病患者拔牙后的失血量和输血需求。两组患者均未出现副作用。筛查试验表明氨甲环酸对肝脏、肾脏或心脏无毒性作用。
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