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麦角生物碱抑制产后泌乳:一项双盲研究。

Suppression of puerperal lactation with an ergot alkaloid: a double-blind study.

作者信息

Varga L, Lutterbeck P M, Pryor J S, Wenner R, Erb H

出版信息

Br Med J. 1972 Jun 24;2(5816):743-4. doi: 10.1136/bmj.2.5816.743.

DOI:10.1136/bmj.2.5816.743
PMID:4556543
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1788467/
Abstract

A double-blind trial was performed in 60 women to establish the effectiveness of an ergot alkaloid, 2-Br-alpha-ergocryptine (ergocryptine; CB 154), in suppressing puerperal lactation and to compare it with stilboestrol and a placebo. At the doses selected ergocryptine and stilboestrol were equally effective.

摘要

对60名女性进行了一项双盲试验,以确定麦角生物碱2-溴-α-麦角隐亭(麦角隐亭;CB 154)在抑制产后泌乳方面的有效性,并将其与己烯雌酚和安慰剂进行比较。在所选择的剂量下,麦角隐亭和己烯雌酚的效果相同。

相似文献

1
Suppression of puerperal lactation with an ergot alkaloid: a double-blind study.麦角生物碱抑制产后泌乳:一项双盲研究。
Br Med J. 1972 Jun 24;2(5816):743-4. doi: 10.1136/bmj.2.5816.743.
2
[Postpartal lactation inhibition by 2-Br-alpha-ergocryptine: I. A comparative study with 2-Br-alpha-ergocryptine in different dosages and placebo (author's transl)].2-溴-α-麦角隐亭对产后泌乳的抑制作用:I. 不同剂量的2-溴-α-麦角隐亭与安慰剂的对比研究(作者译)
Geburtshilfe Frauenheilkd. 1974 Oct;34(10):882-4.
3
An ergocryptine as a lactation inhibitor.麦角隐亭作为一种泌乳抑制剂。
Gynecol Invest. 1974;5(3):133-8. doi: 10.1159/000301647.
4
[Inhibition of puerperal lactation with ergot alkaloids].[麦角生物碱对产后泌乳的抑制作用]
Schweiz Med Wochenschr. 1972 Sep 9;102(36):1284-5.
5
Serum prolactin and the suppression of lactation.
Br J Obstet Gynaecol. 1976 Sep;83(9):679-82. doi: 10.1111/j.1471-0528.1976.tb00912.x.
6
The inhibition of prolactin secretion in man by CB-154 (2-Br-alpha-ergocryptine).CB - 154(2 - 溴 - α - 麦角隐亭)对人体催乳素分泌的抑制作用。
J Clin Endocrinol Metab. 1972 Nov;35(5):768-71. doi: 10.1210/jcem-35-5-768.
7
A new approach to the inhibition of puerperal lactation.一种抑制产后泌乳的新方法。
J Obstet Gynaecol Br Commonw. 1973 Nov;80(11):945-51. doi: 10.1111/j.1471-0528.1973.tb02954.x.
8
[Postpartal lactation inhibition by 2-Br-alpha-ergocryptine: II. A comparative study with 2-Br-alpha-ergocryptine and methallenoestrol (author's transl)].2-溴-α-麦角隐亭对产后泌乳的抑制作用:II. 2-溴-α-麦角隐亭与美他烯雌醇的比较研究(作者译)
Geburtshilfe Frauenheilkd. 1974 Oct;34(10):885-7.
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Prolactin inhibition and suppression of puerperal lactation by a Br-erocryptine (CB 154). A comparison with estrogen.溴隐亭(CB 154)对催乳素的抑制作用及对产后泌乳的抑制:与雌激素的比较。
Obstet Gynecol. 1973 Jun;41(6):884-90.
10
The effectiveness of stilboestrol in the suppression on postpartum lactation.己烯雌酚在抑制产后泌乳方面的有效性。
J Obstet Gynaecol Br Commonw. 1968 Mar;75(3):313-5. doi: 10.1111/j.1471-0528.1968.tb02084.x.

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Metergoline versus bromocriptine in the prevention of puerperal lactation. A double-blind clinical trial.
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Prolactin-lowering and -releasing drugs. Mechanisms of action and therapeutic applications.降低和释放催乳素的药物。作用机制及治疗应用。
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Galactorrhoea: successful treatment with reduction of plasma prolactin levels by brom-ergocryptine.溢乳症:用溴隐亭成功治疗,血浆催乳素水平降低。
Br Med J. 1972 Sep 16;3(5828):669-72. doi: 10.1136/bmj.3.5828.669.

本文引用的文献

1
[2-Br-alpha-ergokryptin: influence on fertility and lactation in the rat].[2-溴-α-麦角隐亭:对大鼠生育力和泌乳的影响]
Experientia. 1968 Nov 15;24(11):1130-1. doi: 10.1007/BF02147804.
2
Oestrogens and puerperal thrombosis.雌激素与产褥期血栓形成
Br Med J. 1968 Dec 21;4(5633):769. doi: 10.1136/bmj.4.5633.769-a.
3
Inhibition of lactation by oestrogens.雌激素对泌乳的抑制作用。
Br Med J. 1968 Nov 9;4(5627):387. doi: 10.1136/bmj.4.5627.387.
4
Puerperal thromboembolism.产褥期血栓栓塞症
Br Med J. 1968 Nov 16;4(5628):451. doi: 10.1136/bmj.4.5628.451-a.
5
Puerperal thromboembolism in relation to the inhibition of lactation by oestrogen therapy.产褥期血栓栓塞与雌激素疗法抑制泌乳的关系。
Br Med J. 1968 Oct 5;4(5622):19-25. doi: 10.1136/bmj.4.5622.19.
6
Increased factor IX levels in puerperium during administration of diethylstilboestrol.在服用己烯雌酚期间产褥期因子IX水平升高。
Br Med J. 1968 Mar 30;1(5595):801-3. doi: 10.1136/bmj.1.5595.801.
7
Effects of ergocornine and ergocryptine on growth of 7,12-dimethylbenzanthracene-induced mammary tumors in rats.麦角柯宁碱和麦角隐亭对7,12-二甲基苯并蒽诱导的大鼠乳腺肿瘤生长的影响。
Cancer Res. 1971 Jul;31(7):1051-3.
8
[Inhibition of prolactin secretion by ergocornine and 2-Br-alpha-ergocryptine: direct action on the hypophysis in culture].麦角隐亭和2-溴-α-麦角隐亭对催乳素分泌的抑制作用:对培养垂体的直接作用
Ann Endocrinol (Paris). 1971 Jan-Feb;32(1):188-92.
9
Suppression of mammary hyperplastic nodule formation and pituitary prolactin secretion in mice induced by ergocornine or 2-bromo-a-ergocryptine.麦角隐亭或2-溴-α-麦角隐亭诱导的小鼠乳腺增生性结节形成及垂体催乳素分泌的抑制作用
J Natl Cancer Inst. 1970 Dec;45(6):1105-12.
10
Prolactin: evidence that it is separate from growth hormone in human blood.
Science. 1970 Nov 13;170(3959):745-7. doi: 10.1126/science.170.3959.745.