合成促黄体生成素释放激素（LH/FSH-RH）对月经紊乱女性的影响。
Effect of synthetic luteinizing hormone releasing hormone (LH/FSH-RH) in women with menstrual disorders.
作者信息
Newton J, Collins W P
出版信息
Br Med J. 1972 Jul 29;3(5821):271-3. doi: 10.1136/bmj.3.5821.271.
Abstract
Synthetic luteinizing hormone/follicle stimulating hormone-releasing hormone (LH/FSH-RH) (50 mug) was given intravenously to six women with oligomenorrhoea and to four women with secondary amenorrhoea. Peripheral venous blood was withdrawn at regular intervals over a 24-hour period. The concentrations of LH, FSH, and oestradiol-17beta were determined by radioimmunoassay. In all subjects there was a variable rise in LH (3-16 times the mean basal level): in six a small rise in FSH (two to three times the mean basal level) and in seven a twofold to threefold rise in oestradiol three to eight hours after the rise in gonadotrophins.
摘要
将合成促黄体生成素/促卵泡激素释放激素（LH/FSH-RH）（50微克）静脉注射给6名月经过少的女性和4名继发性闭经的女性。在24小时内定期采集外周静脉血。通过放射免疫测定法测定LH、FSH和雌二醇-17β的浓度。在所有受试者中，LH均有不同程度的升高（为基础平均水平的3 - 16倍）：6名受试者FSH有小幅升高（为基础平均水平的2 - 3倍），7名受试者在促性腺激素升高后3至8小时雌二醇升高2至3倍。
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