Röher H D, Goretzki P, Horeyseck G
Chir Forum Exp Klin Forsch. 1979:251-4.
After resection of euthyroid goiter, different doses of thyroxine administration for prophylaxis against recurrence were tested and compared. Group 1 (n = 30) received 1 mg L-thyroxine weekly; group 2 (n = 31), 0.1 mg L-thyroxine daily. The intermittent, high-dose thyroxine turned out to be equally effective as the conventional daily intake and showed no negative side effects.
在切除甲状腺功能正常的甲状腺肿后,对不同剂量的甲状腺素给药用于预防复发进行了测试和比较。第1组(n = 30)每周接受1毫克左甲状腺素;第2组(n = 31)每天接受0.1毫克左甲状腺素。结果表明,间歇性高剂量甲状腺素与传统的每日摄入量同样有效,且未显示出负面副作用。