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犬腹腔神经节切除术和星状神经节切除术对胃黏膜神经支配及胃酸分泌的影响。

Effects of celiacectomy and stellatectomy on gastric mucosal innervation and acid secretion in the dog.

作者信息

Larson G M, Ahlman B H, Sano M, Bombeck C T, Nyhus L M

出版信息

Chir Forum Exp Klin Forsch. 1979:93-6. doi: 10.1007/978-3-642-67291-0_18.

Abstract

The effect of surgical excision of the celiac and superior mesenteric ganglia and the stellate ganglia, respectively, on gastric acid secretion and adrenergic innervation of gastric mucosa was studied in five dogs. After removal of the abdominal ganglia, there was a significant increase in acid secretion while there was a marked decrease in the number of adrenergic nerve terminals in the mucosa. When, addition, the stellate ganglia were excised, acid secretion increased slightly in two dogs, while little change in mucosal innervation was noted. These data suggest that the adrenergic innervation of the stomach has an inhibitory role in the control of acid secretion in the dog. Vagal adrenergic nerve fibers seem to be of limited importance in gastric acid production.

摘要

分别切除五只犬的腹腔神经节、肠系膜上神经节和星状神经节,研究其对胃酸分泌及胃黏膜肾上腺素能神经支配的影响。切除腹部神经节后,胃酸分泌显著增加,而黏膜中肾上腺素能神经末梢数量显著减少。此外,切除星状神经节后,两只犬的胃酸分泌略有增加,而黏膜神经支配变化不大。这些数据表明,犬胃的肾上腺素能神经支配在胃酸分泌控制中起抑制作用。迷走神经肾上腺素能神经纤维在胃酸分泌中似乎作用有限。

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