Volosin M, Celis M E
Endocrinology. 1979 Aug;105(2):541-3. doi: 10.1210/endo-105-2-541.
Pseudopregnancy (PSP) was induced in rats by vaginal stimulation and the levels of MSH in serum and pituitary were examined. One hour after vaginal stimulation, the serum MSH level was increased, and a cyclical variation was observed by the second day of PSP. There were two surges of about 50 pg/ml, one in the morning and the other at night. On the sixth day of PSP, the pattern of serum levels still showed two peaks, but while the nocturnal peak remained at 50 pg/ml, the diurnal value was halved. The pituitary MSH content also underwent cyclical variations; the lowest levels coincided with the peak levels in serum. These observations raise the possibility that MSH is involved in PSP.
通过阴道刺激诱导大鼠假孕，并检测血清和垂体中促黑素（MSH）的水平。阴道刺激1小时后，血清MSH水平升高，在假孕第2天观察到周期性变化。有两次约50 pg/ml的峰值，一次在早晨，另一次在夜间。在假孕第6天，血清水平模式仍显示两个峰值，但夜间峰值保持在50 pg/ml，而白天的值减半。垂体MSH含量也发生周期性变化；最低水平与血清中的峰值水平一致。这些观察结果增加了促黑素参与假孕的可能性。
