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体外致敏的贴壁和非贴壁小鼠淋巴结细胞对同基因甲基胆蒽诱导肉瘤的肿瘤相关抗原的细胞介导细胞毒性。

Cell-mediated cytotoxicity of adherent and non-adherent mouse lymph node cells sensitized in vitro against tumour-associated antigens of syngenetic methylcholanthrene-induced sarcomas.

作者信息

Indrová M, Bubeník J

出版信息

Folia Biol (Praha). 1979;25(2):137-41.

PMID:456694
Abstract

Cell-mediated cytotoxicity of adherent and non-adherent subpopulations of mouse lymph node cells sensitized in vitro on monolayers of syngeneic, methylcholanthrene-induced sarcoma cells was examined by inhibition of 3H-thymidine incorporation. The cell-mediated cytotoxicity of nylon wood-adherent, non-adherent and unfractionated lymph node cells was found to be equally efficient.

摘要

通过抑制³H-胸腺嘧啶核苷掺入,检测了在同基因、甲基胆蒽诱导的肉瘤细胞单层上体外致敏的小鼠淋巴结细胞贴壁和非贴壁亚群的细胞介导细胞毒性。发现尼龙柱黏附的、非黏附的和未分离的淋巴结细胞的细胞介导细胞毒性同样有效。

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