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囊性脊柱裂。270例连续病例的治疗结果及未来的选择标准。

Spina bifida cystica. Results of treatment of 270 consecutive cases with criteria for selection for the future.

作者信息

Lorber J

出版信息

Arch Dis Child. 1972 Dec;47(256):854-73. doi: 10.1136/adc.47.256.854.

Abstract

The disappointing results of treatment in 270 consecutive unselected cases of spina bifida admitted during a 27-month period are detailed. Massive effort has led to much avoidable suffering at an exorbitant cost in manpower and money. This study confirms the validity of those adverse prognostic criteria defined in an earlier study and which form a basis for selection. These are (1) thoracolumbar lesions, (2) severe paraplegia, (3) gross enlargement of head, (4) kyphosis, and (5) other severe congenital defects, or birth injuries. It is shown again that selection is possible on the first day of life on purely objective criteria; that it is essential for the benefit of all those affected—whether they are for treatment or no treatment; and that it is in the interest of their families and the community.

摘要

详细介绍了在27个月期间连续收治的270例未经挑选的脊柱裂病例令人失望的治疗结果。巨大的努力导致了大量本可避免的痛苦,耗费了高昂的人力和财力成本。本研究证实了早期研究中定义的不良预后标准的有效性,这些标准构成了选择的基础。这些标准包括:(1)胸腰段病变;(2)严重截瘫;(3)头部明显增大;(4)脊柱后凸;(5)其他严重先天性缺陷或产伤。再次表明,在出生第一天就可以根据纯粹客观的标准进行选择;这对所有受影响的人(无论是否接受治疗)都是有益的;而且这符合他们的家庭和社区的利益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d2/1648403/89314a347ca2/archdisch00870-0023-a.jpg

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