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通过同时静脉注射前列腺素E2和催产素引产。

Induction of labour by simultaneous intravenous administration of prostaglandin E 2 and oxytocin.

作者信息

Naismith W C, Barr W, MacVicar J

出版信息

Br Med J. 1972 Nov 25;4(5838):461-2. doi: 10.1136/bmj.4.5838.461.

Abstract

In a group of 20 matched primigravid patients labour was induced by forewater amniotomy followed by intravenous oxytocin (Syntocinon) administered in escalating doses. Ten of these patients, in a double-blind trial, also received prostaglandin E(2) infused simultaneously with the oxytocin. In the combined prostaglandin-oxytocin group there was a noticeable reduction in the dosage of oxytocin required to produce effective uterine action, and the duration of labour was also reduced. No side effects were observed.

摘要

在一组20例配对的初产妇中,通过人工破膜(前羊水),随后静脉滴注剂量递增的缩宫素(催产素)来引产。在一项双盲试验中,其中10例患者还在滴注缩宫素的同时静脉滴注前列腺素E₂。在前列腺素-缩宫素联合应用组中,产生有效子宫收缩所需的缩宫素剂量明显减少,产程也缩短。未观察到副作用。

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引用本文的文献

1
Intravenous prostaglandin for induction of labour.
Cochrane Database Syst Rev. 2000;2000(4):CD002864. doi: 10.1002/14651858.CD002864.

本文引用的文献

1
The treatment of missed abortion by high dosage syntocinon intravenous infusion.
J Obstet Gynaecol Br Emp. 1962 Apr;69:277-81. doi: 10.1111/j.1471-0528.1962.tb00042.x.
2
Interaction of E prostaglandins and syntocinon on the pregnant human myometrium.
J Obstet Gynaecol Br Commonw. 1971 Apr;78(4):305-9. doi: 10.1111/j.1471-0528.1971.tb00277.x.
3
Automatic oxytocin infusion equipment for induction of labour.
J Obstet Gynaecol Br Commonw. 1970 Jul;77(7):594-602. doi: 10.1111/j.1471-0528.1970.tb03576.x.
4
Failed induction of labour.
J Obstet Gynaecol Br Commonw. 1971 Nov;78(11):1007-9. doi: 10.1111/j.1471-0528.1971.tb00218.x.
5
Oxytocin release by infused prostaglandin.
Br Med J. 1972 Feb 26;1(5799):543-4. doi: 10.1136/bmj.1.5799.543.
6
Oxytocin administration by a variable-speed infusion pump.
Lancet. 1967 Dec 23;2(7530):1339-40. doi: 10.1016/s0140-6736(67)90920-8.

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