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获得性大疱性表皮松解症的免疫病理学

The immunopathology of epidermolysis bullosa acquisita.

作者信息

Kushniruk W

出版信息

Can Med Assoc J. 1973 May 5;108(9):1143-6.

PMID:4574408
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1941384/
Abstract

The acquired type of epidermolysis bullosa, epidermolysis bullosa acquisita, has a high incidence of associated systemic disorders. Two patients with epidermolysis bullosa acquisita were investigated by clinical, histochemical and immunologic methods. The histochemical findings confirmed earlier reported dermal changes. Both patients had in vivo IgG and the C(3) component of complement localized in the basement-membrane zone.

摘要

获得性大疱性表皮松解症（epidermolysis bullosa acquisita）常伴有多种系统性疾病。我们采用临床、组织化学和免疫学方法对两名获得性大疱性表皮松解症患者进行了研究。组织化学结果证实了先前报道的皮肤改变。两名患者体内的IgG和补体C(3)成分均定位于基底膜带。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/23b46f43f569/canmedaj01667-0070-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/fc6476a3e74a/canmedaj01667-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/d4aed71abb6f/canmedaj01667-0069-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/e8437743b219/canmedaj01667-0069-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/9da8ae1f5ab7/canmedaj01667-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/33f61677e3a6/canmedaj01667-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/23b46f43f569/canmedaj01667-0070-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/fc6476a3e74a/canmedaj01667-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/d4aed71abb6f/canmedaj01667-0069-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/e8437743b219/canmedaj01667-0069-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/9da8ae1f5ab7/canmedaj01667-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/33f61677e3a6/canmedaj01667-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/599c/1941384/23b46f43f569/canmedaj01667-0070-c.jpg

相似文献

1
The immunopathology of epidermolysis bullosa acquisita.获得性大疱性表皮松解症的免疫病理学
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Meta-analysis of the clinical and immunopathological characteristics and treatment outcomes in epidermolysis bullosa acquisita patients.获得性大疱性表皮松解症患者的临床和免疫病理学特征及治疗结局的荟萃分析。
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Epidermolysis bullosa acquisita.获得性大疱性表皮松解症。

本文引用的文献

1
EPIDERMOLYSIS BULLOSA ACQUISITA, DERMAL ELASTOSIS, AMYLOIDOSIS.获得性大疱性表皮松解症、皮肤弹性组织变性、淀粉样变性。
Arch Dermatol. 1964 Aug;90:137-42. doi: 10.1001/archderm.1964.01600020005001.
2
Studies on the pathogenesis of epidermolysis bullosa.大疱性表皮松解症发病机制的研究。
J Invest Dermatol. 1962 Dec;39:551-75. doi: 10.1038/jid.1962.156.
3
Epidermolysis bullosa acquisita. Report of three cases and review of all published cases.获得性大疱性表皮松解症。三例报告及所有已发表病例的综述。
Clin Dermatol. 2012 Jan-Feb;30(1):60-9. doi: 10.1016/j.clindermatol.2011.03.011.
4
Epidermolysis bullosa acquisita: autoimmunity to anchoring fibril collagen.获得性大疱性表皮松解症：锚纤维胶原自身免疫。
Autoimmunity. 2012 Feb;45(1):91-101. doi: 10.3109/08916934.2011.606450. Epub 2011 Sep 28.
5
Autoimmunity against type VII collagen in inflammatory bowel disease.炎症性肠病中对 VII 型胶原的自身免疫。
J Cell Mol Med. 2010 Oct;14(10):2393-403. doi: 10.1111/j.1582-4934.2009.00959.x.
6
Autoimmunity to type VII collagen: epidermolysis bullosa acquisita.对VII型胶原蛋白的自身免疫：获得性大疱性表皮松解症。
Clin Rev Allergy Immunol. 2007 Oct;33(1-2):78-84. doi: 10.1007/s12016-007-0027-6.
7
Disseminated cicatricial pemphigoid in a child and in an adult. Ultrastructural diagnostic criteria and differential diagnosis with special reference to acquired epidermolysis bullosa.
Arch Dermatol Res. 1987;279(6):357-65. doi: 10.1007/BF00412620.
8
[Pathomorphogenesis of blistering in epidermolysis bullosa acquisita and epidermolysis bullosa dystrophica (author's transl)].
Arch Dermatol Res (1975). 1975 Nov 14;254(1):103-12. doi: 10.1007/BF00561541.
Arch Dermatol. 1971 Jan;103(1):1-10. doi: 10.1001/archderm.103.1.1.
4
Histochemical study on the pathogenesis of epidermolysis bullosa acquisita.获得性大疱性表皮松解症发病机制的组织化学研究
Tohoku J Exp Med. 1969 Sep;99(1):9-17. doi: 10.1620/tjem.99.9.
5
Study of cutaneous lupus erythematosus by immunohistochemical methods.采用免疫组织化学方法对皮肤红斑狼疮的研究。
Arch Dermatol. 1968 May;97(5):520-6.