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乳腺钼靶检查假阴性导致乳腺癌诊断延迟。

False negative mammograms causing delay in breast cancer diagnosis.

作者信息

Burns P E, Grace M G, Lees A W, May C

出版信息

J Can Assoc Radiol. 1979 Jun;30(2):74-6.

PMID:457739
Abstract

Eighty patients with negative mammograms and proven breast cancer are described. The incidence of negative mammograms is 5 to 7% of all breast cancer in Northern Alberta. In 30 patients, immediate biopsy because of clinical abnormality, and mastectomy, revealed only 3.3% axillary node involvement. The remaining 50 patients gave a history of finding a lump and then had a negative mammogram. Biopsy was delayed for a mean of 45 weeks. Their incidence of axillary node involvement was 42%. The mean age of both groups of patients was seven to eight years younger than the mean for all breast cancer patients. The implications of such delay on prognosis and survival are obvious. More public and medical education is needed.

摘要

本文描述了80例乳房X线摄影呈阴性但确诊为乳腺癌的患者。在阿尔伯塔省北部,乳房X线摄影呈阴性的情况在所有乳腺癌病例中占比5%至7%。30例因临床异常而立即进行活检并接受乳房切除术的患者中,腋窝淋巴结受累率仅为3.3%。其余50例患者有发现肿块后乳房X线摄影呈阴性的病史。活检平均推迟了45周。他们的腋窝淋巴结受累率为42%。这两组患者的平均年龄比所有乳腺癌患者的平均年龄小7至8岁。这种延迟对预后和生存的影响显而易见。需要更多的公众和医学教育。

相似文献

1
False negative mammograms causing delay in breast cancer diagnosis.乳腺钼靶检查假阴性导致乳腺癌诊断延迟。
J Can Assoc Radiol. 1979 Jun;30(2):74-6.
2
Delayed diagnosis of breast cancer as a result of normal mammograms.
Arch Surg. 1983 Jan;118(1):23-4. doi: 10.1001/archsurg.1983.01390010013003.
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Mammography in hospital patients: use and misuse.
J R Coll Surg Edinb. 1992 Feb;37(1):16-8.
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Analysis of patients with false negative mammography and symptomatic breast carcinoma.乳腺钼靶检查假阴性及有症状乳腺癌患者的分析。
J Surg Oncol. 2007 Nov 1;96(6):457-63. doi: 10.1002/jso.20801.
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False-negative mammograms in patients with breast cancer.乳腺癌患者的乳腺钼靶检查假阴性结果。
Can J Surg. 1981 Jan;24(1):50, 52.
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The misuse of mammography in the management of breast cancer.乳腺钼靶摄影在乳腺癌管理中的误用。
Med J Aust. 1986 Sep 1;145(5):185-7.
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Delayed diagnosis and large size of breast cancer after a false negative mammogram.
Eur J Cancer. 1994;30A(9):1299-302. doi: 10.1016/0959-8049(94)90177-5.
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Previous mammograms in patients with impalpable breast carcinoma: retrospective vs blinded interpretation. 1993 ARRS President's Award.不可触及性乳腺癌患者既往乳房X线照片:回顾性解读与盲法解读。1993年美国放射学会主席奖。
AJR Am J Roentgenol. 1993 Dec;161(6):1167-72. doi: 10.2214/ajr.161.6.8249720.
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Use and abuse of mammography in the early diagnosis of breast cancer.乳腺摄影在乳腺癌早期诊断中的应用与滥用
Can J Surg. 1983 May;26(3):262-3, 265.
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Clinical benefits of mastectomy on treatment of occult breast carcinoma presenting axillary metastases.隐匿性乳腺癌伴腋窝转移行乳房切除术的临床获益。
Breast J. 2010 Jan-Feb;16(1):32-7. doi: 10.1111/j.1524-4741.2009.00848.x.

引用本文的文献

1
Breast cancer.乳腺癌
Can Med Assoc J. 1983 Nov 1;129(9):913-4, 918, 920.
2
The occurrence of interval cancers in the Nijmegen screening programme.奈梅亨筛查项目中间隔期癌症的发生情况。
Br J Cancer. 1989 Jun;59(6):929-32. doi: 10.1038/bjc.1989.196.