Ashhurst D E, Vrbová G
J Cell Sci. 1979 Apr;36:137-54. doi: 10.1242/jcs.36.1.137.
The anterior latissimus dorsi (ALD) muscle of chickens is a slow tonic muscle, while the posterior latissimus dorsi (PLD) is a fast twitch muscle. These muscles on opposite sides of a 3-week-old chick were removed, minced and replaced in the site of the other muscle and left to regenerate. The regenerating muscles were examined at various periods from 4 days onwards and their contractile properties were found to resemble those typical of the muscle they replaced and not the original muscle. The regenerating muscles from 8 days onwards displayed the morphological features of the control muscles in the contralateral site. By 14 days, differentiation was almost complete and neuromuscular junctions were seen. It is suggested that the physiological and morphological characteristics of a muscle are determined by its position and possibly also by its innervation.
鸡的前背阔肌(ALD)是慢肌纤维的紧张性肌肉,而后背阔肌(PLD)是快肌纤维的肌肉。将3周龄雏鸡两侧的这些肌肉切除、切碎,然后移植到另一侧肌肉的位置,使其再生。从第4天开始的不同时间段对再生肌肉进行检查,发现其收缩特性类似于所替代肌肉的典型特性,而非原始肌肉的特性。从第8天开始,再生肌肉呈现出对侧对照肌肉的形态特征。到第14天,分化几乎完成,可见神经肌肉接头。这表明肌肉的生理和形态特征由其位置决定,也可能由其神经支配决定。