Kettman J R
Department of Microbiology, University of Texas Health Science Center at Dallas 75235.
Immunopharmacology. 1978 Dec;1(1):29-37. doi: 10.1016/0162-3109(78)90006-1.
Tilorone (2,7-bis[(diethylamino)ethoxy]fluoren-9-one) can enhance the humoral immune response of mice to SRBC although Tilorone has no effect on functional activity of splenic B cells in the absence of immunogen. Tilorone does not alter the effective level of T cell help but does seem to alter the level of effective suppression. Tilorone seems to be an adjuvant only in the sense of removing a normal homeostatic control mechanism, perhaps suppressor T cells.
泰洛龙（2,7-双[(二乙氨基)乙氧基]芴-9-酮）可增强小鼠对绵羊红细胞的体液免疫反应，尽管在没有免疫原的情况下泰洛龙对脾B细胞的功能活性没有影响。泰洛龙不会改变T细胞辅助的有效水平，但似乎会改变有效抑制的水平。泰洛龙似乎只是在消除一种正常的稳态控制机制（可能是抑制性T细胞）的意义上才是一种佐剂。
