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一种确定生物途径中事件顺序的遗传学方法。

A genetic method for determining the order of events in a biological pathway.

作者信息

Jarvik J, Botstein D

出版信息

Proc Natl Acad Sci U S A. 1973 Jul;70(7):2046-50. doi: 10.1073/pnas.70.7.2046.

Abstract

We describe the application of a simple genetic test that indicates the order of events in a morphogenic or biochemical pathway. The test uses temperature-sensitive (ts) and cold-sensitive (cs) mutants, and it orders the times at which the ts and cs defects are expressed.

摘要

我们描述了一种简单基因检测方法的应用,该方法可指示形态发生或生化途径中事件的顺序。该检测使用温度敏感(ts)和冷敏感(cs)突变体,并确定ts和cs缺陷表达的时间顺序。

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