Jarvik J, Botstein D
Proc Natl Acad Sci U S A. 1973 Jul;70(7):2046-50. doi: 10.1073/pnas.70.7.2046.
We describe the application of a simple genetic test that indicates the order of events in a morphogenic or biochemical pathway. The test uses temperature-sensitive (ts) and cold-sensitive (cs) mutants, and it orders the times at which the ts and cs defects are expressed.
我们描述了一种简单基因检测方法的应用,该方法可指示形态发生或生化途径中事件的顺序。该检测使用温度敏感(ts)和冷敏感(cs)突变体,并确定ts和cs缺陷表达的时间顺序。