Milkman R
Science. 1973 Dec 7;182(4116):1024-6. doi: 10.1126/science.182.4116.1024.
At each of five loci in 829 Escherichia coli clones from 156 samples from diverse natural sources, electrophoretic analysis reveals a prominent mobility class (frequency over 0.70) and 2 to 11 distinct mobility classes at lower frequencies. The frequency distribution of the classes argues against the importance of neutral mutations in allozymic variation. Heterosis is not the universal cause of genic polymorphism.
在来自不同自然来源的156个样本中的829个大肠杆菌克隆的五个位点上，电泳分析显示出一个突出的迁移率类别（频率超过0.70）以及2到11个频率较低的不同迁移率类别。这些类别的频率分布表明中性突变在等位酶变异中并不重要。杂种优势并非基因多态性的普遍原因。
