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青紫霉素对大肠杆菌蛋白质合成的作用方式。

Mode of action of lividomycin on protein synthesis in Escherichia coli.

作者信息

Yamaguchi M, Eda J, Kobayashi F, Mitsuhashi S

出版信息

Antimicrob Agents Chemother. 1973 Sep;4(3):380-2. doi: 10.1128/AAC.4.3.380.

Abstract

Lividomycin specifically inhibited bacterial protein synthesis and had codon misreading activity. Lividomycin, moreover, stimulated the binding of aminoacyl-transfer ribonucleic acid to ribosomes, but did not show any significant effects on the formation of aminoacyl-transfer ribonucleic acid and the puromycin reaction.

摘要

青紫霉素特异性抑制细菌蛋白质合成并具有密码子错读活性。此外,青紫霉素刺激氨酰转移核糖核酸与核糖体的结合,但对氨酰转移核糖核酸的形成和嘌呤霉素反应未显示出任何显著影响。

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