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Methylguanidine, a naturally occurring compound showing mutagenicity after nitrosation in gastric juice.

作者信息

Endo H, Takahashi K

出版信息

Nature. 1973 Oct 12;245(5424):325-6. doi: 10.1038/245325a0.

DOI:10.1038/245325a0
PMID:4586440
Abstract
摘要

相似文献

1
Methylguanidine, a naturally occurring compound showing mutagenicity after nitrosation in gastric juice.甲基胍,一种在胃液中经亚硝化后具有致突变性的天然存在的化合物。
Nature. 1973 Oct 12;245(5424):325-6. doi: 10.1038/245325a0.
2
Identification and property of the mutagenic principle formed from a food-component, methylguanidine, after nitrosation in simulated gastric juice.模拟胃液中亚硝化后由食物成分甲基胍形成的诱变剂成分的鉴定与性质
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Formation of methylnitrosocyanamide from methylguanidine and sodium nitrite in simulated gastric juice and in stomachs of rats: quantitative estimation by a mutagenicity assay.在模拟胃液和大鼠胃中由甲基胍和亚硝酸钠形成甲基亚硝基氰胺:通过致突变性试验进行定量评估。
J Natl Cancer Inst. 1979 Jan;62(1):71-7.
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Mutagenic activity of glycine upon nitrosation in the presence of chloride and human gastric juice: a possible role in gastric carcinogenesis.
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Screening of compounds structurally and functionally related to N-methyl-N'-nitro-N-nitrosoquanidine, a gastric carcinogen.对与胃致癌物N-甲基-N'-硝基-N-亚硝基胍在结构和功能上相关的化合物进行筛选。
Gan. 1974 Feb;65(1):45-54.
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Effect of pH and temperature on nitrosamide-induced mutation in Escherichia coli.
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Mutagen formation after the addition of nitrite to normal human gastric juice.
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Genetic analysis of multiple phenotypic changes in the mutant Salmonella typhimurium LT2, produced by a single treatment with nitrosoguanidine.对经亚硝基胍单次处理产生的鼠伤寒沙门氏菌LT2突变体中多种表型变化的遗传分析。
Sov Genet. 1974 Dec 1;9(2):265-6.
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Effect of mild heating on Salmonella typhimurium containing an R factor.温和加热对含有R因子的鼠伤寒沙门氏菌的影响。
J Gen Microbiol. 1973 Jun;76(2):441-4. doi: 10.1099/00221287-76-2-441.
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Cytochrome P-450 content and the ability of liver microsomes from patients undergoing abdominal surgery to alter the mutagenicity of a primary and secondary carcinogen.腹部手术患者肝脏微粒体的细胞色素P-450含量及改变一级和二级致癌物致突变性的能力。
J Natl Cancer Inst. 1973 Dec;51(6):1761-4. doi: 10.1093/jnci/51.6.1761.

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1
In vivo mutagenic interaction of nitrite and ethylenethiourea.
Experientia. 1975 Feb 15;31(2):214-5. doi: 10.1007/BF01990712.