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微生物将酮泛酰内酯还原为泛酰内酯。

Microbial reduction of ketopantoyl lactone to pantoyl lactone.

作者信息

Lanzilotta R P, Bradley D G, McDonald K M

出版信息

Appl Microbiol. 1974 Jan;27(1):130-4. doi: 10.1128/am.27.1.130-134.1974.

Abstract

The results of a microbial survey study have shown that the ability to reduce added ketopantoic acid (or ketopantoyl lactone) and accumulate pantoic acid (or pantoyl lactone) in the growth medium is widespread among diverse fungi. The reductions generally proceeded with less than full stereoselectivity. However, specific strains of the ascomycete Byssochlamys fulva were found to form D[-]-pantoic acid in unusually high yields and optical purity.

摘要

一项微生物调查研究结果表明,在多种真菌中,能够还原添加的酮泛解酸(或酮泛酰内酯)并在生长培养基中积累泛解酸(或泛酰内酯)的能力很普遍。这种还原反应通常没有完全的立体选择性。然而,已发现子囊菌黄丝衣霉的特定菌株能以异常高的产率和光学纯度形成D-(-)-泛解酸。

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