Gotlieb A I, Crosby D, Lemire G G, Huang S
Can Med Assoc J. 1974 Jan 19;110(2):154-8.
A report is presented of a patient surviving four years with a human cardiac allograft. The allograft arteries showed marked graft arteriosclerosis with intimal fibrocellular proliferation. The arteriosclerotic lesions occurring in the larger epicardial vessels were strikingly similar to spontaneous atherosclerosis. The relationship of the long-term survival to the use of a permanent transvenous pacemaker and of the development of severe vascular lesions to acute rejection and hyperlipemia are discussed.
本文报告了一例接受人类心脏同种异体移植后存活四年的患者。同种异体移植动脉显示出明显的移植血管硬化，伴有内膜纤维细胞增生。发生在较大的心外膜血管中的动脉硬化病变与自发性动脉粥样硬化极为相似。讨论了长期存活与使用永久性经静脉起搏器的关系，以及严重血管病变的发生与急性排斥反应和高脂血症的关系。
