Banik S, Guha P K
J Urol. 1979 Jun;121(6):823-6. doi: 10.1016/s0022-5347(17)57007-x.
One case of embryonal paratesticular sarcoma and 2 cases of leiomyosarcomas are reported. The 13-year-old boy with embryonal sarcoma is well after an orchiectomy and high ligation of the spermatic cord followed by radiotherapy and chemotherapy. A 66-year-old man has been doing well after orchiectomy and hemiscrotectomy for a paratesticular leiomyosarcoma. The third patient had a highly pleomorphic leiomyosarcoma and died 2 months postoperatively. The clinical and histological diagnosis of paratesticular rhabdomyosarcomas and leiomyosarcomas is reviewed and the various therapeutic approaches to these neoplasms are discussed. Retroperitoneal lymph node dissection, radiotherapy and chemotherapy are important adjuncts to orchiectomy in the management of rhabdomyosarcomas. On the contrary, retroperitoneal lymph node dissection and radiotherapy are not indicated in leiomyosarcomas, since these neoplasms tend to metastasize by the hematogenous route and are radioresistant. At the present time we are unable to evaluate chemotherapy in the management of paratesticular leiomyosarcomas.
报告了1例睾丸旁胚胎性肉瘤和2例平滑肌肉瘤。患有胚胎性肉瘤的13岁男孩在睾丸切除、精索高位结扎，随后进行放疗和化疗后情况良好。一名66岁男性在接受睾丸旁平滑肌肉瘤的睾丸切除和阴囊半切除术后情况良好。第三名患者患有高度多形性平滑肌肉瘤，术后2个月死亡。回顾了睾丸旁横纹肌肉瘤和平滑肌肉瘤的临床和组织学诊断，并讨论了这些肿瘤的各种治疗方法。在横纹肌肉瘤的治疗中，腹膜后淋巴结清扫、放疗和化疗是睾丸切除术后的重要辅助手段。相反，平滑肌肉瘤不适合进行腹膜后淋巴结清扫和放疗，因为这些肿瘤倾向于通过血行途径转移且对放疗耐药。目前我们无法评估化疗在睾丸旁平滑肌肉瘤治疗中的作用。
