Bendich A, Borenfreund E, Sternberg S S
Science. 1974 Mar 1;183(4127):857-9. doi: 10.1126/science.183.4127.857.
Penetration of somatic mammalian cells by spermatozoa occurred after simple admixture in culture. With sperm labeled in vivo, autoradiography revealed incorporation of DNA into nuclei of recipient cells, indicating release of DNA after entrance by sperm. This system provides a new approach to study the molecular biology of information transfer and of haploid gene expression.
在培养中简单混合后,精子可穿透哺乳动物体细胞。对体内标记的精子进行放射自显影显示,DNA 被整合到受体细胞的细胞核中,这表明精子进入后会释放 DNA。该系统为研究信息传递和单倍体基因表达的分子生物学提供了一种新方法。