小鼠角化上皮的超微结构研究。IV. 溶酶体的定量研究。

Ultrastructural studies of keratinized epithelia of the mouse. IV. Quantitative studies of lysosomes.

作者信息

Rowden G

出版信息

J Invest Dermatol. 1975 Jan;64(1):4-8. doi: 10.1111/1523-1747.ep12540857.

DOI:10.1111/1523-1747.ep12540857

PMID:45928

Abstract

Electron microscope cytochemical and simple morphometric studies have permitted an estimate to be made of the absolute numbers of lysosomes present in various cell layers of murine epidermis. Most lysosomes appear to be present in basal layer keratinocytes with few being detected in Langerhans cells or in granular layer keratinocytes. The observation that lysosomes are not numerous in any of the strata is discussed with respect to an alternative explanation for the presence of diffuse acid hydrolase activity in the granular layers.

摘要

电子显微镜细胞化学和简单形态计量学研究使得对小鼠表皮各细胞层中溶酶体的绝对数量进行估计成为可能。大多数溶酶体似乎存在于基底层角质形成细胞中，而在朗格汉斯细胞或颗粒层角质形成细胞中检测到的溶酶体较少。关于颗粒层中弥漫性酸性水解酶活性存在的另一种解释，讨论了在任何一层中溶酶体数量都不多这一观察结果。

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