Eimermacher H, Tinnefeld W, Pressler H, Schuster P, Beyer H K
Klin Wochenschr. 1979 Jun 1;57(11):575-9. doi: 10.1007/BF01491136.
Carcinoembryonic antigen (CEA) was assayed in 18 samples of non-malignant and 21 samples of malignant effusions. In 95% of benign effusion CEA activity was found within normal limits and increased only in one case of Klebsiella pneumonia. In 57% of the 21 malignant effusions CEA levels were elevated and in 4 cases elevated titers were first indications of the malignancy of the effusion. In some cases remarkable differences between serum titer and effusion titer were found. Combined measurement of CEA activity in plasma and effusion increases diagnostic value.
对18份非恶性积液样本和21份恶性积液样本进行了癌胚抗原(CEA)检测。在95%的良性积液中,CEA活性在正常范围内,仅在1例克雷伯菌肺炎患者中升高。在21份恶性积液中,57%的CEA水平升高,4例中升高的滴度是积液恶性的最初迹象。在某些情况下,发现血清滴度和积液滴度之间存在显著差异。联合检测血浆和积液中的CEA活性可提高诊断价值。