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[肺癌性淋巴管炎。21例报告(作者译)]

[Carcinomatous lymphangitis of the lung. Report of 21 cases (author's transl)].

作者信息

Cervantes Requena F, Costa Roma J, Vivancos Lleida J, Blajot I, Balcells Gorina A

出版信息

Med Clin (Barc). 1979 Mar 25;72(6):231-5.

PMID:459590
Abstract

Twenty-one cases of carcinomatous lymphangitis of the lung are reported. In diagnosing them clinical, roentgenologic, and histopathologic criteria were used and the clinical, roentgenologic and evolutive findins were considered in order to emphasize the origin of the primitive neoplasm. From this point of view the principal ones turned out to be carcinomas of the breast, stomach, and lung. The absence of carcinoma of the thyroid gland as a source of pulmonary lymphangitis carcinomatosa must be pointed out. The higher incidence of this condition in older people and the clear predominance in the female sex are stressed. From a clinical standpoint the most important data were the existence of cough and dyspnea, which are often associated with the commom presence of enlarged left supraclavicular or axillary lymph nodes. There was a predominant pure interstitial pattern (the most common feature was the presence of Kerley's A or B lines), sometimes coexisting with alveolar impairment and very often with accompanying pleural effusion. The mean survival rate was 2 months, with a maximum of 7 months and a minimum of 3 days. The results of the present series were compared with those of the literature and the most significant and constant fact in both instances was that two thirds of the cases of pulmonary lymphangitis carcinomatosa had their origin in neoplasms of the breast, stomach, and lung.

摘要

报告了21例肺癌性淋巴管炎病例。在诊断过程中,采用了临床、放射学和组织病理学标准,并综合考虑了临床、放射学及病情演变情况,以强调原发肿瘤的起源。从这一角度来看,主要原发肿瘤为乳腺癌、胃癌和肺癌。必须指出,甲状腺癌并非肺淋巴管癌病的来源。强调了该病在老年人中发病率较高且明显以女性居多。从临床角度看,最重要的数据是存在咳嗽和呼吸困难,常伴有左侧锁骨上或腋窝淋巴结肿大。主要表现为单纯的间质型(最常见的特征是出现克氏A线或B线),有时与肺泡损害并存,且常伴有胸腔积液。平均生存率为2个月,最长7个月,最短3天。将本系列病例结果与文献报道结果进行比较,在这两种情况下最显著且一致的事实是,三分之二的肺淋巴管癌病病例起源于乳腺、胃和肺的肿瘤。

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