Luna J, Bofill D, Cabrer B, Grau A, Saladie J M, Simó Camps E
Med Clin (Barc). 1979 Apr 10;72(7):303-5.
The observation of a non-metastatic reactive hepatopathy associated with a hypernephroma in a 39-year-old man who had had fever for 4 months led to a review of the literature and an analysis of basically three aspects of the disorder: a) The various manifestations of carcinoma of the kidney, which include a large number of paraneoplastic clinical symptoms (polycythemia, anemia, prolonged fever, hypercalcemia, hypertension, nefropathy, loss of salt, peripheral neuropathy, and amyloidosis); b) an alteracion of hepatic function known since 1961 which is characterized by an abnormal retention of sulfobromophthalein, increase of alkaline phosphatase, prothrombin decrease, dysproteinemia with hypoalbuminemia, and alpha2-globulin increase. It may or may not be accompanied by enlargement of the liver. c) Criteria of operability of the primary tumor.
对一名39岁男性的观察发现,其患有与肾上腺样瘤相关的非转移性反应性肝病,该患者已发热4个月。这促使我们回顾了文献,并对该疾病的三个基本方面进行了分析:a)肾癌的各种表现,包括大量副肿瘤性临床症状(红细胞增多症、贫血、长期发热、高钙血症、高血压、肾病、失盐、周围神经病变和淀粉样变性);b)自1961年以来已知的肝功能改变,其特征为磺溴酞钠异常潴留、碱性磷酸酶升高、凝血酶原降低、伴有低白蛋白血症的蛋白异常血症以及α2球蛋白升高。它可能伴有或不伴有肝脏肿大。c)原发肿瘤的可手术性标准。