Gilmour M N, Turner G
Appl Microbiol. 1974 Jun;27(6):1134-41. doi: 10.1128/am.27.6.1134-1141.1974.
The inherent pleomorphism of Bacterionema matruchotii resulting from its mode of reproduction was enhanced by temporal effects of culture age and growth condition and by the more lasting effects of rough to intermediate to smooth morphological dissociation. Routine morphological observations with a single growth condition were inadequate to permit unambiguous judgements of culture purity. Multiple criteria were required. Pleomorphism and the undetected presence of contaminants in primary and successive cultures of B. matruchotii can explain the emergence of unrelated bacteria from B. matruchotii reported previously by others and ascribed to genetic instability.
因繁殖方式导致的马氏放线杆菌固有的多形性,会受到培养时间和生长条件的暂时影响,以及从粗糙型到中间型再到光滑型形态解离的更持久影响而增强。在单一生长条件下进行常规形态学观察,不足以对培养物纯度做出明确判断。需要多个标准。马氏放线杆菌初代培养物和传代培养物中的多形性以及未检测到的污染物的存在,可以解释其他人先前报道的、归因于基因不稳定的与马氏放线杆菌无关的细菌的出现。