异克舒令作为一种口服血管扩张剂。
Isoxsuprine as an oral vasodilator.
作者信息
Zsotér T T, Baird R J
出版信息
Can Med Assoc J. 1974 Jun 8;110(11):1260-1.
Abstract
The effect of isoxsuprine, administered orally as a single 20-mg tablet, was compared with that of a placebo in a double-blind crossover study in 12 volunteers with and in 12 without peripheral vascular disease. Isoxsuprine failed to increase blood flow in the calf, foot or hand, and did not alter blood pressure or heart rate significantly. Claudication time was not prolonged after taking the drug. This study does not support the value of oral administration of isoxsuprine as a peripheral vasodilator.
摘要
在一项双盲交叉研究中，对12名患有外周血管疾病和12名未患外周血管疾病的志愿者给予20毫克异舒普林单剂量口服片剂，并与安慰剂进行比较。异舒普林未能增加小腿、足部或手部的血流量，也未显著改变血压或心率。服药后跛行时间未延长。本研究不支持口服异舒普林作为外周血管扩张剂的价值。
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本文引用的文献
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The measurement of volume changes in human limbs.人体四肢体积变化的测量。
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Failure of vasodilator drugs in arteriosclerosis obliterans.血管扩张剂药物治疗闭塞性动脉硬化症无效。
Ann Intern Med. 1972 Jan;76(1):35-9. doi: 10.7326/0003-4819-76-1-35.
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