Eggers T R, Doyle L W, Pepperell R J
Med J Aust. 1979 Mar 24;1(6):213-6.
Intravenously administered salbutamol inhibited premature labour for at least 48 hours in 49 of 76 patients (64%), but was more effective (89%) when the cervical dilatation was less than 2 cm, and no apparent cause for the premature labour was evident. Even when premature labour complicated multiple pregnancy, hydramnios, or followed a small antepartum haemorrhage, suppression of labour could often be achieved for at least 48 hours, thus following the administration of betamethasone or the transfer of the patient to a hospital with intensive care facilities for both mother and child. Treatment with betamethasone, in addition to salbutamol, was associated with a less severe form of respiratory distress syndrome, and did not increase the risk of maternal or fetal infection, except in patients with cervical incompetence when 46.2% of such patients were infected.
静脉注射沙丁胺醇可抑制76例患者中49例（64%）的早产至少48小时，但当宫颈扩张小于2厘米且无明显早产原因时效果更佳（89%）。即使早产并发多胎妊娠、羊水过多或发生少量产前出血，通常也可使宫缩抑制至少48小时，从而在给予倍他米松或将患者转至具备母婴重症监护设施的医院后实现这一点。除沙丁胺醇外，使用倍他米松治疗与较轻型呼吸窘迫综合征相关，且不会增加母体或胎儿感染风险，但宫颈机能不全患者除外，此类患者中有46.2%发生感染。
