Mishkin F S, Johnson P M
Postgrad Med J. 1973 Jul;49(573):487-502. doi: 10.1136/pgmj.49.573.487.
The advantages of lung scanning in suspected pulmonary embolism are its diagnostic sensitivity, simplicity and safety. The ability to delineate regional pulmonary ischaemia, to quantitate its extent and to follow its response to therapy provides valuable clinical data available by no other simple means. The negative scan effectively excludes pulmonary embolism but, although certain of its features favour the diagnosis of embolism, the positive scan inherently lacks specificity and requires angiographic confirmation when embolectomy, caval plication or infusion of a thrombolytic agent are contemplated. The addition of simple ventilation imaging techniques with radioxenon overcomes this limitation by providing accurate analog estimation or digital quantitation of regional ventilation: perfusion (V/Q) ratios fundamental to understanding the pathophysiologic consequences of embolism and other diseases of the lung.
肺部扫描在疑似肺栓塞诊断中的优势在于其诊断敏感性、简便性和安全性。它能够描绘出局部肺缺血情况，量化其程度，并追踪其对治疗的反应，从而提供了其他简单方法无法获得的宝贵临床数据。阴性扫描结果可有效排除肺栓塞，但尽管其某些特征有助于栓塞的诊断，阳性扫描结果本身缺乏特异性，当考虑进行栓子切除术、腔静脉折叠术或溶栓剂输注时，需要血管造影确认。通过使用放射性氙气进行简单的通气成像技术，可以提供区域通气的准确模拟估计或数字量化，从而克服这一局限性，通气：灌注（V/Q）比值对于理解栓塞及其他肺部疾病的病理生理后果至关重要。
