Niethammer D
Monatsschr Kinderheilkd (1902). 1979 Jun;127(6):381-8.
The therapy of inborn or acquired defects of the cellular immune function is still in an experimental stage. Basicly, it is possible to replace the non-functioning T-cells by immunocompetent lymphocytes. Bone marrow, fetal liver and/or thymus, or cultivated thymus can serve as the source of such cells. Under certain conditions humoral factors derived from immunocompetent lymphocytes can induce a lacking immune response. Possibilities as well as limitations of these two therapeutic concepts are discussed.
先天性或后天性细胞免疫功能缺陷的治疗仍处于实验阶段。基本上,可以用具有免疫活性的淋巴细胞替代无功能的T细胞。骨髓、胎肝和/或胸腺,或培养的胸腺可作为此类细胞的来源。在某些条件下,来自具有免疫活性淋巴细胞的体液因子可诱导缺乏的免疫反应。本文讨论了这两种治疗概念的可能性及局限性。