Théroux P, Waters D D, Halphen C, Debaisieux J C, Mizgala H F
N Engl J Med. 1979 Aug 16;301(7):341-5. doi: 10.1056/NEJM197908163010701.
The prognostic value of a limited treadmill exercises test performed one day before hospital discharge after acute myocardial infarction was studied in 210 consecutive patients who had no over heart failure and had been free of chest pain for at least four days. No complications occurred. During a one-year follow-up period 28 of 43 patients (65 per cent) who had chest pain during the test reported angina, as compared with 60 of 167 (36 per cent) who had no chest pain during test (P less than 0.001). The one-year mortality rates were 2.1 per cent (three of 146) in patients without changes in the S-T segment during exercise and 27 per cent (17 of 64) in those with depression of the S-T segment (P less than 0.001). Sudden death occurred in one of 146 (0.7 per cent) patients who showed no change in the S-T segment and in 10 of 64 (16 per cent) with depression of the segment (P less than 0.001). Thus, a limited treadmill exercise test performed before hospital discharge after acute myocardial infarction is safe and can predict mortality in the subsequent year.
对210例急性心肌梗死后出院前一天进行的有限平板运动试验的预后价值进行了研究,这些患者均无明显心力衰竭且至少四天无胸痛。未发生并发症。在一年的随访期内,试验期间有胸痛的43例患者中有28例(65%)报告有心绞痛,而试验期间无胸痛的167例患者中有60例(36%)报告有心绞痛(P<0.001)。运动期间S-T段无变化的患者一年死亡率为2.1%(146例中有3例),S-T段压低的患者一年死亡率为27%(64例中有17例)(P<0.001)。S-T段无变化的146例患者中有1例(0.7%)发生猝死,S-T段压低的64例患者中有10例(16%)发生猝死(P<0.001)。因此,急性心肌梗死后出院前进行的有限平板运动试验是安全的,并且可以预测随后一年的死亡率。