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A structural modification study of the antimalarial 2-(p-chlorophenyl)-2-(4-piperidyl)tetrahydrofuran.

作者信息

McCaustland D J, Chien P L, Burton W H, Cheng C C

出版信息

J Med Chem. 1974 Sep;17(9):993-1000. doi: 10.1021/jm00255a019.

DOI:10.1021/jm00255a019
PMID:4606154
Abstract
摘要

相似文献

1
A structural modification study of the antimalarial 2-(p-chlorophenyl)-2-(4-piperidyl)tetrahydrofuran.
J Med Chem. 1974 Sep;17(9):993-1000. doi: 10.1021/jm00255a019.
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Synthesis and antimalarial effects of 1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3-piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine and related substances.1-(3,4-二氯苯基)-3-(4-((1-乙基-3-哌啶基)氨基)-6-甲基-2-嘧啶基)胍及其相关物质的合成与抗疟作用
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Antimalarials. 2. Alpha-di-n-butylaminomethyl-2-(p-chlorophenyl)-5-quinazolinemethanol.抗疟药。2. α-二正丁基氨基甲基-2-(对氯苯基)-5-喹唑啉甲醇
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Synthesis and screening of potential antimalarial agent alpha-(2-piperidyl)-2-(1-adamantyl)-6,8-dichloro-4-quinolinemethanol hydrochloride.潜在抗疟药α-(2-哌啶基)-2-(1-金刚烷基)-6,8-二氯-4-喹啉甲醇盐酸盐的合成与筛选
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The chemotherapy of rodent malaria. XII. Substituted tetrahydrofurans, a new chemical family of antimalarials. The action of 2-(p-chlorophenyl)-2-(4-piperidyl)-tetrahydrofuran against Plasmodium berghei and Plasmodium chabaudi.
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Antimalarials. 9. (2-Piperidyl)-4-quinolinemethanols carrying 2-aroxy and 2-(p-chloroanilino) groups.抗疟药。9. 带有2-芳氧基和2-(对氯苯胺基)基团的(2-哌啶基)-4-喹啉甲醇。
J Med Chem. 1973 May;16(5):528-32. doi: 10.1021/jm00263a027.
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Structure and antimalarial activity of aminoalcohols and 2-(p chlorophenyl)-2-(4-piperidyl)tetrahydrofuran.
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Synthesis and properties of fluorine-containing heterocyclic compounds. 8. -(2-Pyridyl)- and -(2-piperidyl)-2-(trifluoromethyl)-4-azaphenanthrenemethanols.
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Antimalarial activity and conformation of erythro- and threo- -(2-piperidyl)-3,6-bis(trifluoromethyl)-9-phenanthrenemethanol.赤式和苏式-(2-哌啶基)-3,6-双(三氟甲基)-9-菲甲醇的抗疟活性和构象
J Med Chem. 1972 Feb;15(2):207-8. doi: 10.1021/jm00272a024.

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Activities of the tetrahydrofuran derivative, BA-41,799, against Plasmodium cynomolgi infections in rhesus monkeys.四氢呋喃衍生物BA - 41,799对恒河猴食蟹猴疟原虫感染的活性。
Antimicrob Agents Chemother. 1985 Feb;27(2):146-50. doi: 10.1128/AAC.27.2.146.